Phenanthrenes and derivatives
Apexbio Technology LLC Hypericin 548-04-9 10mg
Hypericin (CAS 548-04-9) is a small-molecule inhibitor targeting protein kinase C (PKC) and monoamine oxidase (MAO) It acts to selectively inhibit these enzymes thereby regulating cellular signal transduction pathways related to cell proliferation and apoptosis Hypericin exerts its biological activity primarily through selective inhibition of PKC In in vitro assays hypericin demonstrates an inhibitory profile with IC50 values against PKC ranging from approximately 100 to 250 nM depending on assay conditions Based on these pharmacological properties hypericin holds research potential in oncology virology and neuroscience
Medchemexpress LLC SKF 38393 hydrochloride | 62717-42-4 | MFCD00069248 | >98.0% | 291.77 g/mol | C16H18ClNO2 | 200MG
SKF 38393 hydrochloride is the hydrochloride salt of SKF-38393, a selective dopamine D1 receptor agonist with a reported IC50 of approximately 110 nM. Supplied as a research-grade solid analytical standard, it is used for in vitro pharmacology, receptor binding, and analytical assays. Not for human or clinical use.
- Selective D1 receptor agonist, reported IC50 ≈ 110 nM.
- Hydrochloride salt form improves solubility for biological assays.
- Molecular weight 291.77 g/mol.
- Chemical formula C16H18ClNO2.
- Provided as a solid analytical standard suitable for in vitro studies.
- Typical purities reported ≥98% by HPLC from third-party suppliers.
- Not for human or clinical use; for research only.
Medchemexpress LLC Hypericin | 548-04-9 | 504.443 | 1 MG
Hypericin is a naturally occurring substance found in Hypericum perforatum L. It functions as an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase, and CYP (cytochrome P450). It exhibits antitumor, antiviral, and antidepressive activities, and can induce apoptosis.
- Inhibits PKC (protein kinase C)
- Inhibits MAO (monoaminoxidase)
- Inhibits dopamine-beta-hydroxylase
- Inhibits reverse transcriptase
- Inhibits telomerase
- Inhibits CYP (cytochrome P450)
- Shows antitumor activity
- Shows antiviral activity
- Shows antidepressive activity
- Induces apoptosis
- Relevant for infection research
- Relevant for neurological disease research
- Relevant for cancer research
Cayman Chemical ArIstolochIc AcId 25mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | 99.3% | 524.5 g·mol⁻¹ | C22H27Cl2N7O2S | 200 MG
Dasatinib hydrochloride is a research-grade, ATP-competitive dual Src and Bcr-Abl kinase inhibitor supplied as the hydrochloride salt. It exhibits subnanomolar to low-nanomolar activity against its targets and is intended for laboratory and preclinical research applications; supplied at high purity for analytical use.
- High purity: 99.31%.
- Potent dual Src and Bcr-Abl inhibition at subnanomolar to low-nanomolar concentrations.
- Supplied as the hydrochloride salt in solid form for research use.
- Suitable for research and analytical applications; not for human consumption.
- Available in multiple pack sizes, including 200 MG.
Chem-Impex International, Inc. 9,10-Phenanthrenequinone | MFCD00001163 | 100G
9,10-Phenanthrenequinone, MFCD00001163, 100G
Medchemexpress LLC Pazopanib hydrochloride | 635702-64-6 | 100.0% | 200 MG
Pazopanib hydrochloride is the hydrochloride salt of pazopanib, provided as a high-purity analytical standard intended for research and analytical applications (not for human use).
- High purity confirmed by LCMS (99.99%).
- Hydrochloride salt form for consistent analytical performance.
- Molecular formula C21H24ClN7O2S, molecular weight 473.98 g/mol.
- Available in small-scale packages suitable for assay and method development.
- Suitable as a reference standard for LC/MS, HPLC, and biochemical assays.
Selleck Chemical LLC Malonic acid S3029-100mg
Malonic acid (MOA) one of the major dicarboxylic acids (DCAs) in aerosols has been identified experimentally and computationally to be a strong acid Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters
Accela Chembio Inc Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Medchemexpress LLC 6-aminochrysene | 2642-98-0 | MFCD00003699 | 99.7% | 243.30 g/mol | C18H13N | 50 MG
6-Aminochrysene is an aromatic amine research compound (CAS 2642-98-0) used in laboratory studies. The light yellow solid has molecular formula C18H13N and a molecular weight of 243.30 g/mol. The supplier lists high purity, DMSO solubility data, storage recommendations for powder and solutions, and multiple small pack sizes for research use.
- Light yellow to yellow solid appearance.
- Molecular formula C18H13N and molecular weight 243.30 g/mol.
- High purity (99.7%).
- Soluble in DMSO (100 mg/mL); sonication recommended.
- Recommended storage conditions provided for powder and in-solution forms.
- Available in small research pack sizes, including 50 mg.